Tragedy strikes when headlong social activist Lester Partlow interjects himself into a violent neighborhood altercation. In the aftermath, he blames the broken local government for failing his community and campaigns for office to overhaul city policies.

As he climbs the political ladder, shaking up City Hall in the process, he makes enemies amongst the elites and on the streets, leaving him a man alone, torn between his commitment to community and his hunger for higher seats of power.

A cross between The Wire and House of Cards, Run This City is a political drama series about a tragic hero grappling with themes of identity, betrayal, guilt, and ambition in a city discarded by the rest of society. Yet he believes Baltimore has the potential to become America's next big epicenter of change under his leadership.